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Ketamine Does Not Rescue Plaque Load Gap Detection in the 5XFAD Mouse Model of Alzheimer’s Disease: Histology data

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ID: 002037DRAFT
Contact Wehr, Michael
File Count 6510
Size 5.9 GB
Created October 23, 2026
Last update October 24, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

Raw widefield fluorescence images of Aβ42 immunolabeling and DAPI in brain sections from hemizygous 5XFAD mice, supporting Wright AL, Weible AP, Estes OB, Wehr M (2025) "Ketamine does not rescue plaque load or gap detection in the 5XFAD mouse model of Alzheimer's disease," Frontiers in Aging Neuroscience 17:1505908 (doi:10.3389/fnagi.2025.1505908; PMCID PMC11830726). The histology validates the...

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Keywords:
Alzheimer’s disease, 5XFAD, amyloid beta, Aβ42, ketamine, plaque load, auditory cortex, pontine reticular nucleus, immunohistochemistry, fluorescence microscopy
Contributors
Wehr, Michael
Funding information
National Institute on Aging
- Award Number: R01 AG077681
National Institute of Neurological Disorders and Stroke
- Award Number: R01NS127305
Anatomy
Related resources
Amyloid Pathology in the Central Auditory Pathway of 5XFAD Mice Appears First in Auditory Cortex
ID: doi:10.3389/fnagi.2025.1505908
Resource Type: dcite:JournalArticle
Relation: dcite:IsDescribedBy
Assets Summary
Data Standard
Brain Imaging Data Structure (BIDS)
RRID:SCR_016124
Number Of Samples
1
Number Of Subjects
26
Dandiset Actions
Files
Owners
Mike Wehr
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