Mouse V1 multiplane two-photon imaging with Xenium spatial transcriptomics of the same neurons

This dataset connects the activity of neurons in mouse primary visual cortex (VISp) to their molecular cell type.

We recorded the activity of neurons in awake, head-fixed mice with a multiplane two-photon mesoscope. We recorded 8 imaging planes at about 10.7 Hz per plane. Each mouse had 4 imaging sessions:

1 natural-movie session: 55 movie clips and one repeated test clip. 3 drifting-grating...