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Data supporting "Social Exclusion Amplifies Behavioral Responses to Physical Pain via Insular Neuromodulation"

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ID: 001839DRAFT
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Created May 12, 2026
Last update May 28, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

This dataset contains calcium imaging, simultaneous behavioral data, and fiber photometry data from male mice in NWB format. The calcium imaging was performed in the anterior insular cortex (aIC) and simultaneously recorded behavioral data were obtained during a social exclusion task. Fiber photometry was used to capture oxytocinergic, dopaminergic and endocannabinoid dynamics within the aIC...

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Keywords:
aIC
C57BL/6J mice
physical pain
social pain
neuromodulator
Contributors
Keyes, Laurel ORCID logo
Jia, Caroline ORCID logo
Tran, Andrea
Aloboudi, Faith
Say, Ella
Thao, Nick
Lee, Christopher R. ORCID logo
Batra, Kanha ORCID logo
Nguyen, Amanda
Bal, Aneesh
Nono, Nathaniel N.
Delahanty, Jeremy
Chan, May G.
Patel, Reesha R. ORCID logo
Wichmann, Romy ORCID logo
Taschbach, Felix ORCID logo
Li, Yulong
Benna, Marcus ORCID logo
Pereira, Talmo D. ORCID logo
Li, Hao ORCID logo
Tye, Kay M. ORCID logo
Funding information
Salk Institute for Biological Sciences
Howard Hughes Medical Institute
Kavli Foundation
Clayton Foundation
Dolby Family Fund
National Institute of Health
- Award Number: NIMH R01-MH115920, NIMH R37-MH102441, NICCIH Pioneer Award DP1-AT009925, NIMH 1RF1MH132653-0, ) NIDA R00DA055111
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