Injection of alpha-synuclein preformed fibrils into mouse M2 cortex impairs corticostriatal glutamate transmission compared to monomer injected mice
ID: 001835
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Contact Menard, Marissa
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Created May 6, 2026
Last update May 6, 2026
Licenses: spdx:CC-BY-4.0
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Ex-vivo slice recordings from mice co-injected with AAV8-hSyn-hChR2-tdTOMATO and either monomeric a-synuclein or synuclein preformed fibrils (PFFs) in the M2 cortex were assessed 6w post-injection via optogenetic stimulation of cortical afferents. This dataset includes data from whole--cell patch clamp recordings including spontaneous and evoked EPSCs, paired-pulse ratios, asynchronous synaptic...
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