Noxious stimulation and baseline recordings of ON, OFF and Neutral cells in the rat rostral ventromedial medulla
ID: 001708
DRAFT
DRAFT
Contact Ashworth, Carl
File Count 101
Size 85.8 MiB
Created January 30, 2026
Last update February 4, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
Dataset consisting of single-electrode recordings in lightly anesthetized Sprague-Dawley rats, during both unstimulated periods of activity lasting roughly 25 minutes, and multiple episodes of noxious hind paw stimulation with heat ramp and noxious pinch. For the accompanying preprint see https://doi.org/10.64898/2025.12.15.693905.
Keywords:
Nociception
Descending Pain Modulation
Rostral Ventromedial Medulla
Pain
single-neurons
Multi-Timescale Dynamics
noxious stimulation
brainstem
ON-cells
OFF-cells
Medulla
rat
Defensive Behaviour
reflex
Subject matter:
Rostral Ventromedial Medulla
Contributors
Funding information
National Institutes of Health
- Award Number: NS098660, NS120486
MRC Career Development Award
- Award Number: MR/T010614/1
UKRI Advanced Pain Discovery Platform grant
- Award Number: MR/ W027593/1
EPSRC/MRC Programme Grant
- Award Number: UKRI1970
National Institute of Dental and Craniofacial Research
- Award Number: F31 DE030677
EPSRC DTP
- Award Number: EP/W524633/1
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