Hippocampal CA2 Perineuronal Net Degradation and Social Memory Deficits in a 5XFAD Alzheimer’s Disease Mouse Model

This dataset contains raw and processed experimental data supporting the findings reported in Chaunsali et al. (2025), Alzheimer’s & Dementia, DOI:10.1002/alz.70813. The study investigates the disruption of perineuronal nets (PNNs) in the hippocampal CA2 region of the 5XFAD Alzheimer’s disease mouse model and its association with selective loss of social cognition memory. Included are:...