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Transcranial Focused Ultrasound Stimulation Targeting White Matter Inhibits Seizures in a Rat Model of Epilepsy

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ID: 001683DRAFT
Contact Gao, Huan
File Count 318
Size 331.3 GiB
Created December 11, 2025
Last update December 22, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

In this dataset, we recorded 32-channel EEG and 64-channel intracranial signals from wild-type male rats and male rats with seizures induced by repeated 4-AP injections to investigate the effects of white-matter-targeted transcranial focused ultrasound (tFUS) on seizure inhibition. The 4-AP cocktail was injected into the right S1, and intracranial recordings were obtained from the left S1. The...

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Contributors
Gao, Huan
Frake, Annabel
Durand, Dominique M
He, Bin
Funding information
NIH NS131069
NIH NS124564
NIH NS096761
NIH NS127849-01A1
NIH EB029365
Assets Summary
Species
Rattus norvegicus - Norway rat
Approach
electrophysiological approach
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
23
Variable Measured
ElectrodeGroup
ElectricalSeries
Measurement Technique
multi electrode extracellular electrophysiology recording technique
surgical technique
Dandiset Actions
Files
Metadata
Manifest
Owners
huangao067
Annabel Frake
Versions
DRAFT
Dec 22, 2025
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