Public Dandisets

Transcranial Focused Ultrasound Stimulation Targeting White Matter Inhibits Seizures in a Rat Model of Epilepsy

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DOI: 10.48324/dandi.001683/0.260109.2104
ID: 0016830.260109.2104
Contact Gao, Huan
File Count 318
Size 355.7 GB
Created January 9, 2026
Last update January 9, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

In this dataset, we recorded 32-channel EEG and 64-channel intracranial signals from wild-type male rats and male rats with seizures induced by repeated 4-AP injections to investigate the effects of white-matter-targeted transcranial focused ultrasound (tFUS) on seizure inhibition. The 4-AP cocktail was injected into the right S1, and intracranial recordings were obtained from the left S1. The...

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Contributors
Gao, Huan
Frake, Annabel
Durand, Dominique M
He, Bin
Funding information
NIH NS131069
NIH NS124564
NIH NS096761
NIH NS127849-01A1
NIH EB029365
Assets Summary
Species
Rattus norvegicus - Norway rat
Approach
electrophysiological approach
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
23
Variable Measured
ElectrodeGroup
ElectricalSeries
Measurement Technique
multi electrode extracellular electrophysiology recording technique
surgical technique
Dandiset Actions
Files
Owners
huangao067
Annabel Frake
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