Pyramidal tract and corticostriatal neuron recordings in MPTP-treated macaque performing visuomotor tasks
ID: 001636
DRAFT
DRAFT
Contact Turner, Robert
File Count 447
Size 6.4 GB
Created November 11, 2025
Last update May 18, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
Longitudinal single-unit electrophysiology recordings from the primary motor cortex of two rhesus macaque monkeys (Macaca mulatta), acquired both before and after induction of parkinsonism by systemic MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) intoxication. Recordings span two subjects (Leu, recorded in 1993; Venus, recorded between 1999 and 2000), covering both the healthy baseline...
Keywords:
visuomotor
Pyramidal tract neurons
corticostriatal neurons
MPTP
macaque
electrophysiology
Parkinsonism
primary motor cortex
stretch reflex
PT neurons
IT neurons
Extratelencephalic neurons
Intratelencephalic neurons
cortical projection neurons
Subject matter:
primary motor cortex
middle cerebellar peduncle
striatum
thalamus
ventral thalamus
elbow
arm
Parkinson's disease
Parkinsonism
cerebral peduncle
putamen
Funding information
National Institute of Neurological Disorders and Stroke
- Award Number: NS044551
National Institutes of Health
- Award Number: NS044551
Aligning Science Across Parkinson's (ASAP)
- Award Number: ASAP-020519
National Institute of Neurological Disorders and Stroke
- Award Number: NS070865
National Institutes of Health
- Award Number: NS070865
National Institute of Neurological Disorders and Stroke
- Award Number: NS055197
National Institutes of Health
- Award Number: NS055197
National Institute of Neurological Disorders and Stroke
- Award Number: NS076405
National Institutes of Health
- Award Number: NS076405
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Assets Summary
Approach
electrophysiological approach
behavioral approach
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Subjects
2
Variable Measured
ElectrodeGroup
SpatialSeries
ProcessingModule
Units
ElectricalSeries
Measurement Technique
spike sorting technique
surgical technique
analytical technique
behavioral technique
multi electrode extracellular electrophysiology recording technique