Neurovascular impulse response function (IRF) during spontaneous activity differentially reflects intrinsic neuromodulation across cortical regions
DOI:
10.48324/dandi.001543/0.260130.1715
10.48324/dandi.001543/0.260130.1715
ID: 001543
0.260130.1715
0.260130.1715
Contact Rauscher, Bradley
File Count 196
Size 6.8 TB
Created January 30, 2026
Last update January 30, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
Ascending neuromodulatory projections from deep brain nuclei generate internal brain states that differentially engage specific neuronal cell types. Because neurovascular coupling is cell-type specific and neuromodulatory transmitters have vasoactive properties, we hypothesized that the impulse response function (IRF) linking spontaneous neuronal activity with hemodynamics would depend on...
Keywords:
Neurovascular coupling
Norepinephrine
Acetylcholine
Hemodynamics
Functional connectivity
Funding information
No funding information provided.
Anatomy
No anatomical information provided.
This Dandiset does not specify which brain regions or anatomical structures it covers. Adding indexed anatomy (e.g. UBERON terms) in the metadata editor makes this dataset discoverable by anatomical location.
Assets Summary
Approach
behavioral approach
microscopy approach; cell population imaging
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Subjects
19
Variable Measured
ProcessingModule
ImagingPlane
OnePhotonSeries
OpticalChannel
PlaneSegmentation
BehavioralTimeSeries
Measurement Technique
analytical technique
surgical technique
one-photon microscopy technique
behavioral technique