Mapping of blood flow and slow speckle tissue dynamics using laser speckle contrast imaging

Laser speckle contrast imaging (LSCI) is a wide-field optical technique commonly used to monitor cerebral blood flow (CBF). Recently, we have discovered that besides the fast-decorrelating signals from blood flow, LSCI can also detect slow-decorrelating signals associated with cellular activity. The ability to image these signals has significant implications for various research areas such as...