Data supporting "Social isolation recruits amygdala–medial prefrontal cortex projections to escalate alcohol drinking in male mice"
DOI:
10.48324/dandi.001454/0.260911.2319
10.48324/dandi.001454/0.260911.2319
ID: 001454
0.260911.2319
0.260911.2319
Contact Keyes, Laurel R
File Count 359
Size 104.7 GB
Created September 11, 2026
Last update September 11, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
This dandiset contains data used in the publication: Patel, R.R., Kim, K.N., Patarino, M. et al. Social isolation recruits amygdala–medial prefrontal cortex projections to escalate alcohol drinking in male mice. Nat Neurosci (2026). https://doi.org/10.1038/s41593-026-02413-x. This dandiset includes in vivo calcium imaging of the basolateral amygdala-medial prefrontal cortex circuit in mice...
Keywords:
mouse model
BLA-mPFC Circuit
social isolation
social rank
Alcohol Use Disorder (AUD) Susceptibility
alcohol drinking
Basolateral Amygdala (BLA)
Medial Prefrontal Cortex (mPFC)
calcium imaging
optogenetics
Subject matter:
Prelimbic Cortex (PrL)
Basolateral amygdalar nucleus, anterior part (BLAa)
Contributors
Patel, Reesha R
Kim, Kelly
Patarino, Makenzie 
Paminuan, Rachelle
Taschbach, Felix H.
Li, Hao
Joo, Bitna
Palle, Anna
Yu, Xianru
Lee, Christopher R.
van Hoek, Aniek
White, Jesse
Castro, Rogelio
Cazares, Christian
Miranda, Raymundo L.
Jia, Caroline
Delahanty, Jeremy
Batra, Kanha
Libster, Avraham
Wichmann, Romy
Pereira, Talmo D
Benna, Marcus K
National Institute of Mental Health
NIH/NIMH Blueprint D-SPAN Award
NIH/NIAAA
NIH/NIGMS IRACDA Award
NIH/NIDA K99/R00 Pathway to Independence Award
Brain and Behavior Research Foundation Young Investigator Grant
Whitehall Foundation Grant
Funding information
Salk Institute for Biological Studies
Howard Hughes Medical Institute
The Kavli Foundation
Dolby Family Fund
NIH Office of the Director Pioneer Award
- Award Number: Pioneer Award DP1-AT009925 (NCCIH)
National Institute of Mental Health
- Award Number: R37 (MH102441)
National Institute of Mental Health
- Award Number: R01MH115920 (NIMH)
NIH/NIMH Blueprint D-SPAN Award
- Award Number: K00 (MH132569)
NIH/NIAAA
- Award Number: RO1AA031656
NIH/NIGMS IRACDA Award
- Award Number: K12 (GM068524)
NIH/NIDA K99/R00 Pathway to Independence Award
- Award Number: K99 DA055111
NIH/NIDA K99/R00 Pathway to Independence Award
- Award Number: K99/R00 (AA029180)
Brain and Behavior Research Foundation Young Investigator Grant
Whitehall Foundation Grant
Anatomy
Prelimbic Cortex (PrL)
Basolateral amygdalar nucleus, anterior part (BLAa)
Related resources
Assets Summary
Approach
microscopy approach; cell population imaging
behavioral approach
electrophysiological approach
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Subjects
78
Variable Measured
OnePhotonSeries
ImagingPlane
ProcessingModule
BehavioralEvents
PlaneSegmentation
OpticalChannel
CurrentClampSeries
CurrentClampStimulusSeries
Measurement Technique
analytical technique
behavioral technique
one-photon microscopy technique
surgical technique
current clamp technique