Hippocampal Neural Dynamics and Postoperative Delirium-Like Behavior in Aged Mice
ID: 001428
DRAFT
DRAFT
Contact Shen, Shiqian
File Count 6
Size 26.1 GB
Created April 29, 2025
Last update May 1, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
Using a model of POD in older mice, we investigated the effects of anesthesia/surgery on electrophysiological signals and assessed neural dynamics through in vivo calcium imaging. Additionally, we treated older mice with indole 3-propionic acid (IPA) and evaluated its impact on POD-like behavior, as well as on neural activity using electrophysiology and calcium imaging.
Keywords:
POD Electrophysiology Aging
Contributors
Guo, Shiqi 
Funding information
National Institutes of Health (NIH)
- Award Number: 4 R01 AG 070141-02
National Institutes if Health (NIH)
- Award Number: R01 AG082975
National Institutes if Health (NIH)
- Award Number: R35 GM128692
Anatomy
No anatomical information provided.
This Dandiset does not specify which brain regions or anatomical structures it covers. Adding indexed anatomy (e.g. UBERON terms) in the metadata editor makes this dataset discoverable by anatomical location.
Assets Summary
Approach
electrophysiological approach
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Subjects
5
Variable Measured
ElectrodeGroup
ElectricalSeries
Measurement Technique
surgical technique
multi electrode extracellular electrophysiology recording technique