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Functional properties of corticothalamic circuits targeting paraventricular thalamic neurons

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ID: 001292DRAFT
Contact Fabricio H. Do Monte
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Created January 19, 2025
Last update January 19, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

Corticothalamic projections to sensorimotor thalamic nuclei show modest firing rates and serve to modulate the activity of thalamic relay neurons. By contrast, here we find that high-order corticothalamic projections from the prelimbic (PL) cortex to the anterior paraventricular thalamic nucleus (aPVT) maintain high-frequency activity and evoke strong synaptic excitation of aPVT neurons in rats....

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Keywords:
active avoidance; defensive behavior; depolarization block; feedforward inhibition; food seeking; midline thalamus; prelimbic prefrontal cortex; short-term synaptic plasticity; thalamic reticular nucleus.
Contributors
Guillermo Aquino-Miranda
Dounya Jalloul
Xu O. Zhang
Sa Li
Gilbert J. Kirouac
Michael Beierlein
Fabricio H. Do Monte
Funding information
Anatomy
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