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Characterization of Plasma Membrane Polarization in Hippocampal Neurons During Sine Wave and Modulated Sine Wave Stimulation

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DOI: 10.48324/dandi.001274/0.250805.1401
ID: 0012740.250805.1401
Contact Silkuniene, Giedre
File Count 232
Size 25 GB
Created August 5, 2025
Last update August 5, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

This experimental series aimed to visualize and characterize plasma membrane (PM) polarization dynamics in hippocampal neurons exposed to 2 kHz sine waves or 2 kHz sine waves modulated at 100 Hz or 154 Hz. Neurons were pre-loaded with FluoVolt potentiometric dye to enable visualization of membrane polarization changes. This study was partially supported by the NIH Brain Initiative (NEI...

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Contributors
Silkuniene, Giedre ORCID logo
Kim, Vitalii ORCID logo
Semenov, Iurii ORCID logo
Pakhomov, Andrei ORCID logo
Funding information
National Institutes of Health
- Award Number: 5R21EY034803
National Institutes of Health
- Award Number: 1R21EY034258
Anatomy
Related resources
Excitation and polarization of isolated neurons by high-frequency sine waves for temporal interference stimulation
ID: doi.org/10.1016/j.xcrp.2025.102660
Resource Type: dcite:JournalArticle
Relation: dcite:IsPublishedIn
Assets Summary
Species
Rattus norvegicus - Norway rat
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
20
Associated Projects
Next Gen Temporal Interference Stimulation Non-Invasive Neuromodulation
Identifier: 5R21EY034803
Targeted Neuromodulation by Nanosecond Pulsed Electric Fields
Identifier: 1R21EY034258
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