Public Dandisets

Kinetics of Membrane Charging and Its Dependence on Neuron Shape and Alignment with the Electric Field

0
DOI: 10.48324/dandi.001273/0.250805.1356
ID: 0012730.250805.1356
Contact Silkuniene, Giedre
File Count 181
Size 10.6 GB
Created August 5, 2025
Last update August 5, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

This experimental series aimed to visualize and characterize plasma membrane (PM) polarization dynamics in hippocampal neurons exposed to 2 µs electric pulses, focusing on the influence of neuronal shape and position within the applied electric field. Neurons were pre-loaded with FluoVolt potentiometric dye, and pulsed laser strobe microscopy was employed to capture changes in membrane...

[ + see more ]
Contributors
Silkuniene, Giedre ORCID logo
Kim, Vitalii ORCID logo
Semenov, Iurii ORCID logo
Pakhomov, Andrei ORCID logo
Funding information
National Institutes of Health
- Award Number: 5R21EY034803
National Institutes of Health
- Award Number: 1R21EY034258
Anatomy
Related resources
Excitation and polarization of isolated neurons by high-frequency sine waves for temporal interference stimulation
ID: doi.org/10.1016/j.xcrp.2025.102660
Relation: dcite:IsPublishedIn
Assets Summary
Species
Rattus norvegicus - Norway rat
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
13
Associated Projects
Next Gen Temporal Interference Stimulation Non-Invasive Neuromodulation
Identifier: 5R21EY034803
Targeted Neuromodulation by Nanosecond Pulsed Electric Fields
Identifier: 1R21EY034258
Dandiset Actions
Files
Owners
GiedreSilk
Versions