Tetrodotoxin Blockade of Sodium Channels Abolishes Action Potential Formation During Intense Sinewave Stimulation
DOI:
10.48324/dandi.001271/0.250805.1352
10.48324/dandi.001271/0.250805.1352
ID: 001271
0.250805.1352
0.250805.1352
Contact Silkuniene, Giedre
File Count 287
Size 203.1 MB
Created August 5, 2025
Last update August 5, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
This dataset explores whether blocking sodium channels with tetrodotoxin (TTX) can prevent action potential formation during intense sinewave stimulation. Applying 1 µM TTX suppressed action potentials, as expected, and completely prevented sustained depolarization. This study was partially supported by the NIH Brain Initiative (NEI R21EY034803).
Funding information
National Institutes of Health
- Award Number: 5R21EY034803
National Institutes of Health
- Award Number: 1R21EY034258
Anatomy
No anatomical information provided.
This Dandiset does not specify which brain regions or anatomical structures it covers. Adding indexed anatomy (e.g. UBERON terms) in the metadata editor makes this dataset discoverable by anatomical location.
Related resources
Assets Summary
Associated Projects
Next Gen Temporal Interference Stimulation Non-Invasive Neuromodulation
Targeted Neuromodulation by Nanosecond Pulsed Electric Fields