Public Dandisets

Individualized Target Selection of Closed-loop Electrical Stimulation for the Treatment of Spontaneous Temporal Lobe Epilepsy.

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DOI: 10.48324/dandi.001212/0.241023.0931
ID: 0012120.241023.0931
Contact Kedi, Xu
File Count 56
Size 3.6 GB
Created October 23, 2024
Last update October 23, 2024
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

We provided a comprehensive dataset from a study involving 4-channel long-term brain electrophysiological recordings from 7 pilocarpine-treated rats, each subjected to 4 baseline and 4 stimulation groups. Each group was monitored over a period of 5 to 10 days, with a minimum of 6 spontaneous seizures recorded. The baseline groups captured spontaneous seizures without therapeutic stimulation,...

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Keywords:
neurophysiology
neurosurgery
local field potential
spontaneous seizures
multi-site
NWB
temporal lobe epilepsy
Subject matter:
Sprague-Dawley
dentate gyrus (DG)
CA1 subfield of the hippocampus (CA1)
CA3 subfield of the hippocampus (CA3)
anterior nucleus of the thalamus (ANT)
Contributors
Yufang, Yang
Yuting, Sun
Yanjie, Xing
Haoqi, Ni ORCID logo
Chang, Wang
Jianmin, Zhang
Junming, Zhu
Kedi, Xu ORCID logo
Funding information
STI 2030—Major Projects
- Award Number: 2021ZD0200405
National Natural Science Foundation of China
- Award Number: 82272112
Outstanding Youth Program of Zhejiang Natural Science Foundation
- Award Number: LR23H180002
Key R&D Program of Zhejiang
- Award Number: 2023C03078
5510 Project of the second affliated hospital of Zhejiang Univeristy
- Award Number: 551001852022
the Starry Night Science Fund of Zhejiang University Shanghai Institute for Advanced Study
- Award Number: SN-ZJU-SIAS-002
Anatomy
dentate gyrus (DG)
CA1 subfield of the hippocampus (CA1)
CA3 subfield of the hippocampus (CA3)
anterior nucleus of the thalamus (ANT)
Related resources
Progressive alterations in electrophysiological and epileptic network properties during the development of temporal lobe epilepsy in rats
Resource Type: dcite:JournalArticle
Relation: dcite:Cites
Assets Summary
Species
Rattus norvegicus - Norway rat
Approach
electrophysiological approach
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
7
Variable Measured
ElectricalSeries
ElectrodeGroup
Measurement Technique
surgical technique
multi electrode extracellular electrophysiology recording technique
Dandiset Actions
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Metadata
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Owners
SancTUARY-Ni
Versions
DRAFT
Oct 23, 2024
0.241023.0931
Oct 23, 2024