Neurovascular impulse response function (IRF) during spontaneous activity differentially reflects intrinsic neuromodulation across cortical regions
ID: 001211
DRAFT
DRAFT
Contact Rauscher, Bradley
File Count 77
Size 2.2 TB
Created October 19, 2024
Last update October 21, 2024
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
Ascending neuromodulatory projections from deep brain nuclei generate internal brain states that differentially engage specific neuronal cell types. Because neurovascular coupling is cell-type specific and neuromodulatory transmitters have vasoactive properties, we hypothesized that the impulse response function (IRF) linking spontaneous neuronal activity with hemodynamics would depend on...
Keywords:
Neurovascular coupling
Norepinephrine
Acetylcholine
Hemodynamics
Functional connectivity
Contributors
Fomin-Thunemann, Natalie 
Kura, Sreekanth
Perez, Pablo
Martin, Emily
Balog, Dora
Chai, Nathan
Froio, Francesca
Bloniasz, Patrick
Tang, Rockwell
Garcia, Andrew
Jiang, John
Gavornik, Jeffrey
Kleinfeld, David
Hasselmo, Michael
Lewis, Laura
Sakadzic, Sava
Tian, Lei
Mishne, Gal
Stephen, Emily
Thunemann, Martin
Boas, David
Devor, Anna
Funding information
National Institute of Health
- Award Number: BRAIN Initiative U19NS123717
National Institute of Health
- Award Number: BRAIN Initiative R01NS122742
National Institute of Health
- Award Number: R01DA050159
National Institute of Health
- Award Number: T32-NS136080
Boston University Kilachand Fund
Boston University Neurophotonics Center
Anatomy
No anatomical information provided.
This Dandiset does not specify which brain regions or anatomical structures it covers. Adding indexed anatomy (e.g. UBERON terms) in the metadata editor makes this dataset discoverable by anatomical location.
Assets Summary
Approach
behavioral approach
microscopy approach; cell population imaging
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Subjects
9
Variable Measured
BehavioralTimeSeries
PlaneSegmentation
OpticalChannel
ProcessingModule
ImagingPlane
Measurement Technique
surgical technique
behavioral technique
analytical technique