Separable Dorsal Raphe Dopamine Projections Mediate the Facets of Loneliness-like State
DOI:
10.48324/dandi.001195/0.250408.1733
10.48324/dandi.001195/0.250408.1733
ID: 001195
0.250408.1733
0.250408.1733
Contact Keyes, Laurel
File Count 230
Size 70 GB
Created April 8, 2025
Last update April 8, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
Supporting data for the publication "Separable Dorsal Raphe Dopamine Projections Mediate the Facets of Loneliness-like State" by Christopher R. Lee, Gillian A. Matthews, Mackenzie E. Lemieux, Elizabeth M. Wasserlein, Matilde Borio, Raymundo L. Miranda, Laurel R. Keyes, Gates P. Schneider, Caroline Jia, Andrea Tran, Faith Aloboudi, May G. Chan, Enzo Peroni, Grace S. Pereira, Alba López-Moraga,...
Keywords:
optogenetics
behavior videos
calcium imaging
electrophysiology
Social Isolation
Social Motivation
mouse behavior
behavioral neuroscience
mouse model
Dorsal Raphe Nucleus (DRN)
Dopamine neurons
Subject matter:
dorsal raphe nucleus (DRN)
Central Amygdala (CeA)
Bed Nucleus of the Stria Terminalis (BNST)
Posterior Basolateral Amygdala (BLP)
social isolation
Funding information
The JPB Foundation
New York Stem Cell Foundation
Klingenstein Third Generation Foundation
McKnight Foundation
Clayton Foundation
Alfred P Sloan Foundation
National Institute of Mental Health
- Award Number: R01-MH115920
National Institute of Diabetes and Digestive and Kidney Diseases: NIH Director's New Innovator Award
- Award Number: DP2-DK102256
National Center for Complementary and Integrative Health Pioneer Award (NCCIH)
- Award Number: DP1-AT009925
Charles A. King Trust Postdoctoral Research Fellowship Program
MIT Summer Research Program, supported by the Center for Brains, Minds and Machines (CBMM)
National Science Foundation Science and Technology Centers Award
- Award Number: CCF-1231216
Dolby Family Fund
Related resources
Assets Summary
Approach
electrophysiological approach
microscopy approach; cell population imaging
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Cells
131
Number Of Samples
8
Number Of Subjects
34
Variable Measured
CurrentClampStimulusSeries
VoltageClampSeries
VoltageClampStimulusSeries
CurrentClampSeries
OpticalChannel
ImagingPlane
PlaneSegmentation
ProcessingModule
OnePhotonSeries
Measurement Technique
voltage clamp technique
current clamp technique
one-photon microscopy technique
analytical technique
surgical technique
Associated Projects
Separable Dorsal Raphe Dopamine Projections Mediate Sociability and Valence