Public Dandisets

Cortical acetylcholine dynamics are predicted by cholinergic axon activity and behavior state

1
ID: 001176DRAFT
Contact Reimer, Jacob
File Count 132
Size 881.4 MiB
Created August 20, 2024
Last update April 27, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

This dataset includes simultaneous in vivo imaging data of acetylcholine (ACh) sensors and GCaMP-expressing axons in the cortex during spontaneous changes in behavioral states in awake animals. It features detailed recordings of ACh activity, axon activity, and pupil size, providing valuable insights into the spatiotemporal properties of cortical ACh release and its correlation with axonal...

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Keywords:
acetylcholine
brain states
two-photon-imaging
neuromodulator
Axon imaging
Contributors
Reimer, Jacob ORCID logo
Neyhart, Erin ORCID logo
Funding information
National Institutes of Health (NIH)
- Award Number: RF1 NS128901
Assets Summary
Species
Mus musculus - House mouse
Approach
microscopy approach; cell population imaging
behavioral approach
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
29
Variable Measured
ImagingPlane
PlaneSegmentation
EyeTracking
PupilTracking
ProcessingModule
OpticalChannel
SpatialSeries
Measurement Technique
behavioral technique
analytical technique
surgical technique
Dandiset Actions
Files
Owners
Ming Hu
Jacob Reimer
Versions
DRAFT
Apr 27, 2025
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