Cortical acetylcholine dynamics are predicted by cholinergic axon activity and behavior state
DOI:
10.48324/dandi.001176/0.260610.2204
10.48324/dandi.001176/0.260610.2204
ID: 001176
0.260610.2204
0.260610.2204
Contact Reimer, Jacob
File Count 132
Size 924.2 MB
Created June 10, 2026
Last update June 10, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
This dataset includes simultaneous in vivo imaging data of acetylcholine (ACh) sensors and GCaMP-expressing axons in the cortex during spontaneous changes in behavioral states in awake animals. It features detailed recordings of ACh activity, axon activity, and pupil size, providing valuable insights into the spatiotemporal properties of cortical ACh release and its correlation with axonal...
Keywords:
acetylcholine
brain states
two-photon-imaging
neuromodulator
Axon imaging
Funding information
National Institutes of Health (NIH)
- Award Number: RF1 NS128901
Assets Summary
Approach
microscopy approach; cell population imaging
behavioral approach
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Subjects
29
Variable Measured
ImagingPlane
PlaneSegmentation
EyeTracking
PupilTracking
ProcessingModule
OpticalChannel
SpatialSeries
Measurement Technique
behavioral technique
analytical technique
surgical technique