Public Dandisets

Mesoscale Two-Photon Calcium Imaging of Population Level Odor Responses from the Mouse Olfactory Bulb

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DOI: 10.48324/dandi.001170/0.251111.1532
ID: 0011700.251111.1532
Contact Reimer, Jacob
File Count 12
Size 327.9 GiB
Created November 11, 2025
Last update November 11, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

This study explores odor-evoked activity representation in the olfactory bulb (OB) and how odor responses enable odor discrimination. Contrary to some previously cited theories that suggest a sparse representation, we hypothesize a more dense representation during odor presentation. A key question is how odors are reliably encoded in OB activity patterns, and how these patterns contribute to...

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Keywords:
odor-evoked activity
olfactory bulb
two photon calcium imaging
Contributors
Pfaffinger, Paul
Hanson, Elizabeth ORCID logo
Pirhayatifard, Delaram
Reimer, Jacob ORCID logo
Hu, Ming
Navlakha, Saket ORCID logo
Arenkiel, Benjamin ORCID logo
Funding information
National Institutes of Health (NIH)
- Award Number: 1 UF1 NS 111692-01
Related resources
Conserved neural dynamics and computations across species in olfaction
ID: https://doi.org/10.1101/2023.04.24.538157
Resource Type: dcite:Preprint
Repo: bioRxiv
Relation: dcite:IsDescribedBy
Dense Odor Coding in the Mouse Olfactory Bulb
Resource Type: dcite:ConferencePaper
Relation: dcite:IsDescribedBy
reimer-arenkiel-lab-to-nwb
ID: https://github.com/catalystneuro/reimer-arenkiel-lab-to-nwb
Resource Type: dcite:Software
Repo: GitHub
Relation: dcite:IsCompiledBy
Assets Summary
Species
Mus musculus - House mouse
Approach
behavioral approach
microscopy approach; cell population imaging
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
8
Variable Measured
SpatialSeries
ProcessingModule
PlaneSegmentation
OpticalChannel
TwoPhotonSeries
ImagingPlane
Measurement Technique
behavioral technique
two-photon microscopy technique
analytical technique
surgical technique
Dandiset Actions
Files
Owners
Ben Dichter
Liz Hanson Moss
Alessandra Trapani
Ming Hu
Jacob Reimer
Versions
0.251111.1532
Nov 11, 2025