Public Dandisets

Mesoscale Two-Photon Calcium Imaging of Population Level Odor Responses from the Mouse Olfactory Bulb

1
ID: 001170DRAFT
Contact Reimer, Jacob
File Count 12
Size 352.1 GB
Created August 8, 2024
Last update May 28, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

This study explores odor-evoked activity representation in the mouse olfactory bulb (OB) using mesoscale two-photon calcium imaging to investigate how odor responses enable discrimination. Contrary to theories suggesting purely sparse representations, we hypothesize a denser population-level representation during odor presentation. The dataset includes population-level odor responses recorded as...

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Keywords:
odor-evoked activity
olfactory bulb
two photon calcium imaging
olfactory system
neural dynamics
biological neural network
sparse coding
odor discrimination
Subject matter:
olfactory bulb
mitral cell
olfactory bulb tufted cell
olfactory granule cell
Contributors
Pfaffinger, Paul
Hanson, Elizabeth ORCID logo
Pirhayatifard, Delaram
Reimer, Jacob ORCID logo
Hu, Ming
Navlakha, Saket ORCID logo
Arenkiel, Benjamin ORCID logo
Funding information
National Institutes of Health (NIH)
- Award Number: 1 UF1 NS 111692-01
National Science Foundation (NSF)
U.S. Department of Defense (DoD)
Office of Naval Research (ONR)
Related resources
Conserved neural dynamics and computations across species in olfaction
ID: https://doi.org/10.1101/2023.04.24.538157
Resource Type: dcite:Preprint
Repo: bioRxiv
Relation: dcite:IsDescribedBy
Dense Odor Coding in the Mouse Olfactory Bulb
Resource Type: dcite:ConferencePaper
Relation: dcite:IsDescribedBy
reimer-arenkiel-lab-to-nwb
ID: https://github.com/catalystneuro/reimer-arenkiel-lab-to-nwb
Resource Type: dcite:Software
Repo: GitHub
Relation: dcite:IsCompiledBy
Example notebook for Dandiset 001170
Resource Type: dcite:ComputationalNotebook
Relation: dcite:IsSupplementedBy
Assets Summary
Species
Mus musculus - House mouse
Approach
behavioral approach
microscopy approach; cell population imaging
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
8
Variable Measured
SpatialSeries
ProcessingModule
PlaneSegmentation
OpticalChannel
TwoPhotonSeries
ImagingPlane
Measurement Technique
behavioral technique
two-photon microscopy technique
analytical technique
surgical technique
Dandiset Actions
Files
Owners
Ben Dichter
Liz Hanson Moss
Alessandra Trapani
Ming Hu
Jacob Reimer
Versions
DRAFT
May 28, 2026