Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices
DOI:
10.48324/dandi.001132/0.241130.1903
10.48324/dandi.001132/0.241130.1903
ID: 001132
0.241130.1903
0.241130.1903
Contact Andrews, John P.
File Count 69
Size 179.2 GiB
Created November 30, 2024
Last update November 30, 2024
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
High-density microelectrode array (HD-MEA) recordings of human hippocampal brain slices obtained from epilepsy patients, including optogenetic stimulus and several hyperactivity-provoking conditions of culture medium. This data accompanies the manuscript by Andrews, Geng, Voitiuk, et al. 2024.
Keywords:
hippocampus
slice
HD-MEA
optogenetics
epilepsy
epileptiform activity
human hippocampus
responsive neuromodulation
AAV
gene therapy
Subject matter:
epilepsy
hippocampus
Contributors
Geng, Jinghui 
Voitiuk, Kateryna
Elliott, Matthew A. T.
Shin, David
Robbins, Ash
Spaeth, Alex
Wang, Albert
Li, Lin
Solis, Daniel
Keefe, Matthew G.
Sevetson, Jessica L.
Rivera de Jesús, Julio A.
Donohue, Kevin
Larson, H. Hanh
Ehrlich, Drew
Auguste, Kurtis I.
Salama, Sofie R.
Sohal, Vikaas
Sharf, Tal
Haussler, David
Cadwell, Cathryn
Schaffer, David
Chang, Edward F.
Funding information
National Institutes of Health
- Award Number: 5R25NS070680-13, UF1MH130700, R01NS123263, R01MH120295, 5RM1HG011543, T32HG012344, K08NS126573, K12GM139185, LRP0000018281
National Science Foundation
- Award Number: 2034037, CNS-1730158, ACI-1540112, ACI-1541349, OAC-1826967
Schmidt Futures Foundation
- Award Number: SF 857
Weill Neurohub
- Award Number: U01NS132353
Esther A & Joseph Klingenstein Fund
Shurl and Kay Curci Foundation
Sontag Foundation
William K. Bowes, Jr. Foundation
Related resources
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