Public Dandisets

Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior

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DOI: 10.48324/dandi.001084/0.241023.2011
ID: 0010840.241023.2011
Contact Vu, Mai-Anh T.
File Count 180
Size 770 GiB
Created October 23, 2024
Last update October 23, 2024
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

Neural population dynamics relevant to behavior vary over multiple spatial and temporal scales across three-dimensional volumes. Current optical approaches lack the spatial coverage and resolution necessary to measure and manipulate naturally occurring patterns of large-scale, distributed dynamics within and across deep brain regions such as the striatum. We designed a new micro-fiber array...

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Keywords:
multi-site photometry
behaving mice
freely moving mice
striatum
dopamine
neuromodulation
Subject matter:
striatum
dopamine
Contributors
Vu, Mai-Anh T. ORCID logo
Brown, Eleanor H.
Wen, Michelle J.
Noggle, Christian A.
Zhang, Zicheng
Monk, Kevin J.
Bouabid, Safa
Mroz, Lydia
Graham, Benjamin M.
Zhuo, Yizhou
Li, Yulong
Otchy, Timothy M.
Tian, Lin
Davison, Ian G.
Boas, David A.
Howe, Mark W. ORCID logo
Funding information
Michael J. Fox Foundation
- Award Number: ASAP-020370
National Institute of Mental Health
- Award Number: R01 MH125835
Parkinson’s Foundation
- Award Number: PF-SF-JFA-836662
National Institute of Mental Health
- Award Number: F32MH120894
National Institute of Mental Health
- Award Number: 1F31NS127536
National Institute on Deafness and Other Communication Disorders
- Award Number: F32DC020665
National Institute of Neurological Disorders and Stroke​
- Award Number: RF1NS128975
Related resources
Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior
ID: https://doi.org/10.1016/j.neuron.2023.12.011
Resource Type: dcite:JournalArticle
Repo: Neuron
Relation: dcite:IsDescribedBy
howe-lab-to-nwb
Resource Type: dcite:Software
Repo: GitHub
Relation: dcite:IsCompiledBy
NWB tutorial notebook
Resource Type: dcite:ComputationalNotebook
Repo: GitHub
Relation: dcite:IsDescribedBy
Howe Lab GitHub
Resource Type: dcite:Software
Repo: GitHub
Relation: dcite:IsSupplementedBy
Assets Summary
Species
Mus musculus - House mouse
Approach
microscopy approach; cell population imaging
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
16
Variable Measured
OpticalChannel
ImagingPlane
PlaneSegmentation
ProcessingModule
Measurement Technique
analytical technique
surgical technique
Dandiset Actions
Files
Owners
Ben Dichter
Szonja Weigl
Mai-Anh Vu
Versions
0.241023.2011
Oct 23, 2024