Unique functional responses differentially map onto genetic subtypes of dopamine neurons
DOI:
10.48324/dandi.001038/0.241111.1719
10.48324/dandi.001038/0.241111.1719
ID: 001038
0.241111.1719
0.241111.1719
Contact Dombeck, Daniel A.
File Count 1238
Size 21.2 GiB
Created November 11, 2024
Last update November 11, 2024
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
Dopamine neurons are characterized by their response to unexpected rewards, but they also fire during movement and aversive stimuli. Dopamine neuron diversity has been observed based on molecular expression profiles; however, whether different functions map onto such genetic subtypes remains unclear. In this study, we established that three genetic dopamine neuron subtypes within the substantia...
Keywords:
Fiber photometry
GCaMP6f
Dopamine
substantia nigra pars compacta
striatum
Subject matter:
substantia nigra pars compacta
dopaminergic cell groups
Contributors
Funding information
Michael J. Fox Foundation
- Award Number: ASAP-020600
National Institutes of Health
- Award Number: R01MH110556
National Institute of Neurological Disorders and Stroke
- Award Number: 1R01NS119690-01
National Institute on Drug Abuse
- Award Number: P50 DA044121-01A1
National Institute of General Medical Sciences
- Award Number: 5T32GM008152-34
National Cancer Institute
- Award Number: CA060553
Protocols
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