Offline ensemble co-reactivation links memories across days
DOI:
10.48324/dandi.000718/0.260825.1902
10.48324/dandi.000718/0.260825.1902
ID: 000718
0.260825.1902
0.260825.1902
Contact Zaki, Yosif
File Count 20
Size 40.6 GB
Created August 25, 2026
Last update August 25, 2026
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
Memories are encoded in neural ensembles during learning and are stabilized by post-learning reactivation. Integrating recent experiences into existing memories ensures that memories contain the most recently available information, but how the brain accomplishes this critical process remains unclear. Here we show that in mice, a strong aversive experience drives offline ensemble reactivation of...
Keywords:
hippocampus
learning
memory
memory-linking
aversive
ensemble
co-activity
reactivation
offline
Subject matter:
hippocampal formation
memory
learning
Contributors
Bacon, Madeline E.
Funding information
National Institute of Neurological Disorders and Stroke
- Award Number: F32NS116416
National Institute of Neurological Disorders and Stroke
- Award Number: R03 NS111493
National Institute of Neurological Disorders and Stroke
- Award Number: R01NS116357
National Institute of Neurological Disorders and Stroke
- Award Number: R01NS136590
National Institute on Aging
- Award Number: RF1AG072497
National Institute on Aging
- Award Number: R01AG013622
National Institute on Drug Abuse
- Award Number: R21DA049568
National Heart, Lung, and Blood Institute
- Award Number: T32HL160511
National Institute of Mental Health
- Award Number: R01MH113071
National Institute of Mental Health
- Award Number: R01MH120162
National Institute of Mental Health
- Award Number: DP2MH122399
National Institute of Mental Health
- Award Number: F31MH126543
National Institute of Mental Health
- Award Number: R56MH132959
National Institute of Mental Health
- Award Number: K99MH131792
Related resources
Assets Summary
Approach
microscopy approach; cell population imaging
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Subjects
2
Variable Measured
PlaneSegmentation
OpticalChannel
ImagingPlane
ProcessingModule
OnePhotonSeries
Measurement Technique
surgical technique
one-photon microscopy technique
analytical technique