Focusing electroporation to the center of a quadrupole electrode array by interference of unipolar pulses (NextGeneration-CANCAN)

These experimental trials demonstrate the feasibility of achieving remote targeting in electroporation by utilizing sequences of unipolar nanosecond electric pulses (nsEP), with the rotation of these packets further enhancing the process. Electroporation of the cells was evaluated using 1 uM YoPro-1 cell impermeable fluorescent dye. The study was supported in part by R21EY034258 from the National...