Glia Accumulate Evidence that Actions Are Futile and Suppress Unsuccessful Behavior
DOI:
10.48324/dandi.000350/0.240822.1759
10.48324/dandi.000350/0.240822.1759
ID: 000350
0.240822.1759
0.240822.1759
Contact Mu, Yu
File Count 12
Size 5.3 TiB
Created August 22, 2024
Last update August 22, 2024
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess
When a behavior repeatedly fails to achieve its goal, animals often give up and become passive, which can be strategic for preserving energy or regrouping between attempts. It is unknown how the brain identifies behavioral failures and mediates this behavioral-state switch. In larval zebrafish swimming in virtual reality, visual feedback can be withheld so that swim attempts fail to trigger...
Keywords:
neuroscience
glia
astrocytes
norepinephrine
noradrenaline
learned helplessness
neuromodulation
behavioral states
evidence accumulation
zebrafish
Contributors
Funding information
Howard Hughes Medical Institute
- Award Number: 325171
Simons Collaboration on the Global Brain Awards
- Award Number: 542943SPI
Related resources
Assets Summary
Approach
microscopy approach; cell population imaging
Data StandardRRID:SCR_015242
Neurodata Without Borders (NWB)
Number Of Subjects
12
Variable Measured
TwoPhotonSeries
OpticalChannel
ProcessingModule
ImagingPlane
PlaneSegmentation
Measurement Technique
surgical technique
two-photon microscopy technique
analytical technique