Public Dandisets

A metabolic function of the hippocampal sharp wave-ripple

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DOI: 10.48324/dandi.000233/0.250624.0414
ID: 0002330.250624.0414
Contact Tingley, David
File Count 345
Size 11.2 TiB
Created June 24, 2025
Last update June 24, 2025
Licenses: spdx:CC-BY-4.0
Access Information: dandi:OpenAccess

The hippocampus has previously been implicated in both cognitive and endocrine functions. We simultaneously measured electrophysiological activity from the hippocampus and interstitial glucose concentrations in the body of freely behaving rats to identify an activity pattern that may link these disparate functions of the hippocampus. Here we report that clusters of sharp wave-ripples recorded...

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Keywords:
glucose
ecephys
pharmacology
Subject matter:
Type 2 Diabetes
Hippocampus
Hypothalamus
Contributors
Tingley, David ORCID logo
McClain, Kathryn
Kaya, Ekin ORCID logo
Carpenter, Jordan ORCID logo
Buzsáki, György ORCID logo
Funding information
National Institutes of Health
- Award Number: MH122391, U19NS104590, and U19NS107616
Related resources
A metabolic function of the hippocampal sharp wave-ripple
ID: https://doi.org/10.1038/s41586-021-03811-w
Resource Type: dcite:JournalArticle
Repo: Nature
Relation: dcite:IsDescribedBy
Assets Summary
Species
Rattus norvegicus - Norway rat
Approach
electrophysiological approach
Data Standard
Neurodata Without Borders (NWB)
RRID:SCR_015242
Number Of Subjects
25
Variable Measured
ElectricalSeries
ProcessingModule
LFP
ElectrodeGroup
Measurement Technique
multi electrode extracellular electrophysiology recording technique
analytical technique
signal filtering technique
surgical technique
Dandiset Actions
Files
Owners
Ben Dichter
Cody Baker
Peter C. Petersen
Versions
0.250624.0414
Jun 24, 2025